Weekly paper roundup: Week of April 15th

  • A new GPU-based deconvolution plugin for Fiji/ImageJ that promises Richardson-Lucy deconvolution in around a second. [1]
  • A careful comparison of localization between immunofluorescence and fluorescent protein tagging. Gratifyingly, the two methods agree well. [2]
  • A new approach to calculating localization for super-resolution microscopy approaches using high magnification on an EMCCD that claims a 2-fold improvement in accuracy [3]
  • Injectable, wireless, ultrasmall LEDs used for optogenetics in free-running mice [4]


  1. M.A. Bruce, and M.J. Butte, "Real-time GPU-based 3D Deconvolution", Optics Express, vol. 21, pp. 4766, 2013. http://dx.doi.org/10.1364/OE.21.004766
  2. C. Stadler, E. Rexhepaj, V.R. Singan, R.F. Murphy, R. Pepperkok, M. Uhlén, J.C. Simpson, and E. Lundberg, "Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells", Nature Methods, vol. 10, pp. 315-323, 2013. http://dx.doi.org/10.1038/nmeth.2377
  3. J. Chao, S. Ram, E.S. Ward, and R.J. Ober, "Ultrahigh accuracy imaging modality for super-localization microscopy", Nature Methods, vol. 10, pp. 335-338, 2013. http://dx.doi.org/10.1038/nmeth.2396
  4. T. Kim, J.G. McCall, Y.H. Jung, X. Huang, E.R. Siuda, Y. Li, J. Song, Y.M. Song, H.A. Pao, R. Kim, C. Lu, S.D. Lee, I. Song, G. Shin, R. Al-Hasani, S. Kim, M.P. Tan, Y. Huang, F.G. Omenetto, J.A. Rogers, and M.R. Bruchas, "Injectable, Cellular-Scale Optoelectronics with Applications for Wireless Optogenetics", Science, vol. 340, pp. 211-216, 2013. http://dx.doi.org/10.1126/science.1232437