1. How were surface areas calculated?
Surface areas were calculated with the program NACCESS. The program's standard parameters were used: a 1.4 angstrom water probe and the van der Waals radii distributed with the program.

2. How can I download the whole database?
If you you do a search with only the partner type specified, you will return all interactions of that type. Alternatively, a MySQL dump of the database is available.