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Mutated systems in ASEdb:
| Type | Mutated Protein | Partner | PDB entry | Mutations | sysID |
|---|---|---|---|---|---|
| Protein-protein | Ab hu4D5-5 | p185HER2 | 1fvc (monomer) | 22 | 42 |
| Protein-protein | Agitoxin | Shaker | N/A | 11 | 39 |
| Protein-protein | Angiogenin | RNase inhibitor | 1a4y (dimer) | 14 | 2 |
| Protein-protein | Barnase | Barstar | 1brs (dimer) | 8 | 5 |
| Protein-protein | Barstar | Barnase | 1brs (dimer) | 6 | 6 |
| Protein-protein | bFGF | FGFR1b | 4fgf (monomer) | 18 | 56 |
| Protein-protein | BMP type IA receptor | BMP-4 | N/A | 6 | 99 |
| Protein-protein | bovine profilin I | rabbit actin | 1pne (monomer) | 2 | 86 |
| Protein-protein | BPTI | Chymotrypsin | 1cbw (dimer) | 9 | 20 |
| Protein-protein | BPTI | Trypsin | 2ptc (dimer) | 1 | 21 |
| Protein-protein | CD2 | CD48 | 1cdc (monomer) | 14 | 23 |
| Protein-protein | CD4 | gp120 | 1gc1 (dimer) | 49 | 41 |
| Protein-protein | Charybdotoxin | Shaker | N/A | 4 | 26 |
| Protein-protein | Complement C1q | IgG2b | N/A | 9 | 81 |
| Protein-protein | D1.3 | E5.2 | 1dvf (dimer) | 16 | 55 |
| Protein-protein | D1.3 | HEL | 1vfb (dimer) | 17 | 44 |
| Protein-protein | Dendrotoxin K | K+ Channels | N/A | 8 | 11 |
| Protein-protein | E5.2 | D1.3 | 1dvf (dimer) | 9 | 7 |
| Protein-protein | Erabutoxin A | AChR | 5ebx (monomer) | 21 | 29 |
| Protein-protein | Erabutoxin A | Ma2-3 | 5ebx (monomer) | 21 | 30 |
| Protein-protein | Factor VII | Tissue Factor | 1dan (dimer) | 107 | 79 |
| Protein-protein | HEL | D1.3 | 1vfb (dimer) | 12 | 24 |
| Protein-protein | HEL | HYHEL-10 | 3hfm (dimer) | 13 | 38 |
| Protein-protein | hG-CSF | hG-CSFbp | 1rhg (monomer) | 32 | 10 |
| Protein-protein | hGH | hGHbp, site1 | 3hhr (dimer) | 31 | 1 |
| Protein-protein | hGH | hGHbp, site? | 3hhr (dimer) | 31 | 54 |
| Protein-protein | hGH | hPRLbp +Zn | 3hhr (monomer) | 44 | 52 |
| Protein-protein | hGH | hPRLbp -Zn | 3hhr (monomer) | 7 | 53 |
| Protein-protein | hGH | Mab 1 | 3hhr (monomer) | 70 | 58 |
| Protein-protein | hGH | Mab 11 | 3hhr (monomer) | 59 | 60 |
| Protein-protein | hGH | Mab 12 | 3hhr (monomer) | 71 | 61 |
| Protein-protein | hGH | Mab 13 | 3hhr (monomer) | 71 | 62 |
| Protein-protein | hGH | Mab 14 | 3hhr (monomer) | 73 | 63 |
| Protein-protein | hGH | Mab 15 | 3hhr (monomer) | 68 | 64 |
| Protein-protein | hGH | Mab 16 | 3hhr (monomer) | 73 | 65 |
| Protein-protein | hGH | Mab 17 | 3hhr (monomer) | 70 | 66 |
| Protein-protein | hGH | Mab 18 | 3hhr (monomer) | 98 | 67 |
| Protein-protein | hGH | Mab 19 | 3hhr (monomer) | 98 | 68 |
| Protein-protein | hGH | Mab 2 | 3hhr (monomer) | 62 | 69 |
| Protein-protein | hGH | Mab 20 | 3hhr (monomer) | 100 | 70 |
| Protein-protein | hGH | Mab 21 | 3hhr (monomer) | 100 | 71 |
| Protein-protein | hGH | Mab 3 | 3hhr (monomer) | 62 | 72 |
| Protein-protein | hGH | Mab 4 | 3hhr (monomer) | 83 | 73 |
| Protein-protein | hGH | Mab 5 | 3hhr (monomer) | 83 | 74 |
| Protein-protein | hGH | Mab 6 | 3hhr (monomer) | 83 | 75 |
| Protein-protein | hGH | Mab 7 | 3hhr (monomer) | 71 | 76 |
| Protein-protein | hGH | Mab 8 | 3hhr (monomer) | 64 | 77 |
| Protein-protein | hGH | Mab 9 | 3hhr (monomer) | 64 | 78 |
| Protein-protein | hGH | Mab10 | 3hhr (monomer) | 80 | 59 |
| Protein-protein | hGHbp | mAb12B8 | 3hhr (monomer) | 8 | 46 |
| Protein-protein | hGHbp | mAb13E1 | 3hhr (monomer) | 8 | 47 |
| Protein-protein | hGHbp | mAb263 | 3hhr (monomer) | 8 | 48 |
| Protein-protein | hGHbp | mAb3B7 | 3hhr (monomer) | 8 | 49 |
| Protein-protein | hGHbp | mAb3D9 | 3hhr (monomer) | 8 | 50 |
| Protein-protein | hGHbp | mAb5 | 3hhr (monomer) | 8 | 51 |
| Protein-protein | hGHbp, site 1 | hGH | 3hhr (dimer) | 67 | 45 |
| Protein-protein | hIL-18 binding protein | hIL-18 | N/A | 15 | 100 |
| Protein-protein | HYHEL-10 | HEL | 3hfm (dimer) | 3 | 43 |
| Protein-protein | IGF-1 | IGF-1R | 2gf1 (monomer) | 4 | 83 |
| Protein-protein | IGF-1 | IGFbp-1 | 2gf1 (monomer) | 4 | 32 |
| Protein-protein | IL-2 (human) | IL-2 receptor | 3ink (monomer) | 2 | 19 |
| Protein-protein | IL-2 receptor beta (human) | IL-2 (murine) | N/A | 4 | 8 |
| Protein-protein | IL-4 | IL4-BP | 1rcb (monomer) | 18 | 9 |
| Protein-protein | IL-6 | IL-6R | 1il6 (monomer) | 2 | 15 |
| Protein-protein | IL-6 | mAb8 | 1il6 (monomer) | 2 | 16 |
| Protein-protein | IL-8 | IL-8R | 3il8 (monomer) | 4 | 82 |
| Protein-protein | IL-8RA | IL-8 | N/A | 13 | 57 |
| Protein-protein | IL4/IL4bp | Gamma c | N/A | 18 | 37 |
| Protein-protein | Im2 | E9 DNase | N/A | 12 | 33 |
| Protein-protein | Im9 | E9 DNase | 1bxi (dimer) | 28 | 35 |
| Protein-protein | k-conotoxin PVIIA | shaker K+ channel | N/A | 15 | 91 |
| Protein-protein | Kistrin | GP IIb-IIIa | N/A | 43 | 80 |
| Protein-protein | mAb A4.6.1 | VEGF | N/A | 65 | 34 |
| Protein-protein | mIL-2 | mIL-2Ra | N/A | 5 | 4 |
| Protein-protein | NmmI | nAChR | N/A | 1 | 25 |
| Protein-protein | NT-3 | gp75 | 1nt3 (monomer) | 10 | 17 |
| Protein-protein | NT-3 | trkC | 1nt3 (monomer) | 23 | 18 |
| Protein-protein | Protein A | IgG1 | 1fc2 (dimer) | 3 | 84 |
| Protein-protein | RNase inhibitor | Angiogenin | 1a4y (dimer) | 14 | 3 |
| Protein-protein | RNase inhibitor | RNase A | 1dfj (dimer) | 14 | 85 |
| Protein-protein | scTCR Vb | SEC3-1A4 | 1JCK (monomer) | 24 | 87 |
| Protein-protein | SEC3 | TCR Vb | 1jck (dimer) | 10 | 88 |
| Protein-protein | Shaker | Agitoxin | N/A | 3 | 40 |
| Protein-protein | Shaker | CTX | N/A | 1 | 27 |
| Protein-protein | sHIR | Insulin | N/A | 53 | 28 |
| Protein-protein | Tissue Factor | Fab 5G9 | 1ahw (dimer) | 8 | 22 |
| Protein-protein | Tissue Factor | Factor VIIa | 1dan (dimer) | 78 | 31 |
| Protein-protein | VEGF | KDR | N/A | 50 | 12 |
| Protein-protein | VEGF | mAb 3.2E3.1.1 | N/A | 50 | 13 |
| Protein-protein | VEGF | mAb A4.6.1 | N/A | 50 | 14 |
| Protein-protein | yCaM | Calcineurin | N/A | 6 | 36 |
| Protein-DNA/RNA | Mcm1 | Mcm1 binding site DNA | 1mnm (dimer) | 38 | 90 |
| Protein-DNA/RNA | P22 Arc | L1 half site | 1bdt (dimer) | 18 | 97 |
| Protein-DNA/RNA | PI-SceI | PI-SceI recognition site | 1vde (monomer) | 8 | 94 |
| Protein-DNA/RNA | TRAP | trp leader RNA | 1wap (monomer) | 14 | 95 |
| Protein-Small molecule | Endoglucanase C | Avicel | 1ulo (monomer) | 8 | 92 |
| Protein-Small molecule | Endoglucanase C | b-glucan | 1ulo (monomer) | 10 | 93 |
| Protein-Small molecule | human androgen receptor | R1881 | N/A | 8 | 101 |
| Protein-Small molecule | P/CAF bromodomain | H4 acetyllysine peptide | N/A | 4 | 98 |
| Protein-Small molecule | scFv FITC-E2 | fluorescein | N/A | 4 | 89 |
| Protein-Small molecule | TRAP | tryptophan | 1wap (dimer) | 16 | 96 |